This platform focuses on research and development of functionalised metal nanoparticle systems for therapeutics and targeted drug delivery.
The Biolabels unit has developed a range of metal nanoparticles for biological and
pharmaceutical applications (e.g. Gold, silver, etc,) These nanoparticles are produced
by the Unit as semi-
These are produced as important building blocks for nanotechnological applications.
Monolayer Protected Clusters (MPCs):
MPCs are produced specifically to address advanced application by attaching specific functionalized ligands of choice on the nanoparticle core. Biocompatible functional MPCs containing various functional groups such as carboxyl, amine, azide, biotin, nitrilotriacetic acid (NTA) etc. are produced.
Bioconjugates are produced by attaching specific biomolecular functionality or biomargers (proteins, sugars, peptides, enzymes, antibodies, etc.) on the surface of MPCs. They are engineered addressing key issues, such as stability, biocompatibility etc. The nanobioconjugate systems are utilized in various diagnostic and therapeutic applications. Custom conjugation is also offered.
The diagnostic platform focuses on the design and development of rapid diagnostic tests for human and animal diseases and labeling reagents for in vivo imaging.
- The Unit develops a variety of lateral flow devices for the detection of human as well as animal diseases that plague the African continent and beyond.
- The lateral flow tests focus on the detection of antibodies/antigens in the test sample (sera, blood, saliva, urine) using biomarker functionalized gold nanoparticles.
Development of nano-
The labeling reagesnt developed in the Unit are used by our collaborators for research in:
- Diabetes diagnostics
The Unit has world class equipment for synthesis, characterisation and fabrication
of nanomaterials and nano-
Plate reader and washer
To become a leading innovator in the field of nanomedicine.
To develop expertise in the field of nanomedicine or nanotechnology in South Africa.
To develop functionalized metal nanoparticles (or tools) for in-
To design and develop nanotechnology-
Research Focus Area
The Biolabels Development Unit focuses on developing nanomaterials-
General Contact Info
Mintek, SA, Johannesburg
Private Bag X3015
Tel: +27 11 709 4111
Fax: +27 11 793 2413
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